Bioinformatics & Rational Drug Design

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Bioinformatics heralds beginning of new era in the most complex and challenging world of life sciences research that has witnessed dramatic increase in the data volume with the novel application of computational skills and statistical methods for analysis and for modelling. Bioinformatics is the answer for better and faster progress in research.

Bioinformatics with the use of advanced computational technologies allows us to gather, store, analyze, integrate and represent genetic information effectively. It Bioinformatics is associated typically with massive databases of gene and protein structure and function. It also does comparative analysis using remote computer access.

Exponential growth of biological data requires huge amount of storage space and high speed interpretation. This is possible only by computers. Studies on genomes have brought in a surge of information and that is growing every day. The data also needs to be interpreted as in DNA chips and microarrays. Speed computational cataloguing and retrieval of this information has become pertinent in all fields be it medical literature, understanding metabolic pathways, interpreting protein 3D structure, study of phylogeny, pharmacogenetics, drug designing, comparative genomics or agriculture.

Management of these complex datasets is becoming a bottleneck to scientific advances. By giving a global perspective, Bioinformatics can play a pivotal role for biologists.

Scope of bioinformatics

• Improvement in drug designing to suit individual needs, through personalised genomic medicine using clinical informatics.
• Microbial genome research for Bio fuel and environmental clean up
• More accurate risk assessment by gene mapping
• To be able to analyse data in forensics
• Yield better crops
• To improve economy by all the above

Various Industrial giants are involved making this dream a reality. Industries like GVK Biosciences, MNCs like IBM, Biocon, Dr. Reddy’s labs.-DAC, GlaxoSmithKline Pharmaceuticals are actively involved.